Some of the above traditional remedies have been supported by recent laboratory studies. Among these:
Moringa leaf extract has been shown to be effective in lowering blood sugar levels within a space of 3 hours, albeit less effectively than the standard hypoglycaemic drug, glibenclamide. Effects increased with larger doses.30
An extract taken from dried leaves showed an impressive ability to heal ulcers in laboratory animals. Administration of daily doses by injection caused a very significant improvement in the healing rate in induced gastric ulcers.31
An extract made from dried powdered leaves was shown to have a very potent depressive effect on the central nervous system, resulting in significant muscle relaxation, decreased body temperatures and increased sleep time among laboratory mice. Subjects receiving the highest dosages spent twice as much time asleep as the control group.32
An extract from dried roots, applied orally to laboratory mice, demonstrated clearly that the roots possess antiinflammatory properties.33 In another study, infusion of seeds, roots and flowers significantly inhibited the formation of pedal edema, although the authors concluded that the seed infusion may be the only one worthy of further investigation.34
An infusion made from seeds demonstrated an ability to inhibit intestinal spasms, as well as some diuretic activity. However, other plant parts (leaves, roots, stalks and flowers) showed no significant antispasmodic or diuretic activity.35
An in vitro study showed that an aqueous extract made from seeds is effective against Pseudomonas aeruginosa, Staphylococcus aureus and Escheridia coli. This study showed the seed extract to be equally effective as Neomycin against S. aureus. Similar results were obtained with aqueous extracts from the roots.36
Fresh leaf juice has showed some positive inhibition of Pseudomonas aeruginosa37 and an extract from leaves was found to be effective at inhibiting the growth of the fungi Basidiobolus haptosporus and B.ranarum. The in vitro anti-fungal effects of the extract compared favorably the with the effects of some conventional drugs used to treat zygomycotic infections.38
Aqueous extract from stem bark were shown to increase the rate of heart contraction sat low concentrations and decrease the rate at high concentrations, with the effect of lowering blood pressure.39 Moringinine, from root bark, acts on the sympathetic nervous system and acts as a cardiac stimulant, relaxes bronchioles (bronchial tube inflammation) and inhibits involuntary intestinal tract movement. Anthonine, also found in root bark, is highly toxic to the cholera bacterium.40
Spirochin, found in the roots, is anti-gram+ bacteria, analgesic, antipyretic, affects the circulatory system (by raising or lowering heart beat, depending on dose), and affects the nervous system. In high doses it can paralyze the vagus nerve. Also found in roots and seeds, benzylisothiocyanate (which works against fungi and bacteria) may be even better than medicinally utilized benzylisothiocyanate and other isothiocyanates.
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Source: The Miracle Tree by Lowell Fugile, March 2004